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Scientist, Oncology Biomarker Development - Cancer Immunotherapy


South San Francisco, CA 94080
  • Biotechnology / Science
  • Healthcare
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Job Details

We are looking for a highly motivated, experienced and talented scientist to lead biomarker discovery and development strategies for cancer immune-therapy (CIT) programs in Oncology Biomarker Development. The successful candidate is also expected to contribute to data mining and reverse translation efforts to support discovery of new targets and to inform clinical development strategies.

The successfulcandidate should have documented expertise in translational science and development, and implementation of biomarkers in clinical trials. Industry experience is a plus. A deep understanding of Immunology and Cancer Biology is required. A track record of publications in high impact scientific journals is desired. Knowledge and interest in cutting edge technologies such as NGS, multiplex IHC/IF, high dimensional flow cytometry, single cell RNASeq, and big data analysis tools are desirable. Outstanding oral presentation and written skills, ability to work independently and collaborate closely with research, companion diagnostics, and clinical leaders is a must. Ability to lead cross-functional teams is desired. The successful candidate is expected to drive the publication of biomarker data in high quality scientific, technical or medical journals, to represent the department and programs at external meetings, to be a key representative to our investigators, and to promote collaborative efforts to forward the biomarker sciences field in general.

This role requires an individual with passion for helping patients and translational science as well asoutstanding communication and leadership skills.

Primary Responsibilities

  • Provide exceptional scientific leadership to molecule and disease strategy teams, to your peers within OBD and to the organization in general.
  • Design, conduct, and analyze laboratory experiments in the areas of cancer immunotherapy.
  • Design and implement Pharmacodynamic and Diagnostic biomarker strategies for cancer immunotherapy clinical studies within the Roche/Genentech pipeline portfolio.
  • Harness existing study data sets to inform reverse translational research efforts
  • Represent biomarker related strategies and plans to biomarker review forums, decision committees and project teams.
  • Drive biomarker related regulatory strategies and interactions with health authorities around the globe including review of relevant regulatory documents.
  • Drive scientific and technical innovation collaboratively with other members of the department. Participate and thrive in an interactive, team-oriented culture.
  • Represent OBD externally through presentations at key scientific meetings and interactions with investigators.
  • Strive to publish scientific and methodological projects in high quality journals.


  • PhD in a relevant scientific field (e.g. cancer biology, molecular biology, immunology) with a minimum of 5 years post-doctoral experience in industry/academic setting. Industry experience in cancer immunotherapy, translational science and biomarker development is preferred.
  • Expertise in human immunology, cancer immunotherapy, oncology, cancer cell signaling pathways, and translational research is highly desirable.
  • Demonstrated record of scientific leadership as evidenced by first and/or senior authored publications.
  • Experience in translational or clinical drug development including advanced understanding of critical development functions, e.g. Clinical Sciences, Biomarker Development, Translational Medicine, Clinical Pharmacology, Regulatory, Safety, Operations, Biostatistics, Bioinformatics, etc will be an advantage.
  • Outstanding presentation and communication skills.
  • Successful demonstration of initiative, teamwork, collaboration and technical expertise as an independent and creative scientist.
  • Roche is an equal opportunity employer.



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